Aryl hydrocarbon receptor pathway
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:biological_pathway
|
| gptkbp:activatedBy |
dioxins
polycyclic aromatic hydrocarbons |
| gptkbp:discoveredBy |
1976
|
| gptkbp:foundIn |
vertebrates
|
| gptkbp:involves |
gptkb:cancer
gptkb:heat_shock_protein_90 autoimmune diseases ligand binding developmental toxicity DNA binding gene transcription regulation Aryl hydrocarbon receptor XAP2 protein XRE (xenobiotic response element) dimerization with ARNT p23 protein translocation to nucleus AIP (Aryl hydrocarbon receptor-interacting protein) ARNT (Aryl hydrocarbon receptor nuclear translocator) |
| gptkbp:modulatedBy |
endogenous ligands
exogenous ligands |
| gptkbp:regulates |
gptkb:immune_response
cell differentiation cell proliferation xenobiotic metabolism CYP1A1 gene expression |
| gptkbp:relatedTo |
toxicology
environmental health endocrine disruption |
| gptkbp:bfsParent |
gptkb:ARNT
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Aryl hydrocarbon receptor pathway
|