|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
bHLHe76
Ah receptor
Dioxin receptor
|
|
gptkbp:associatedWith
|
cell cycle regulation
immune system regulation
developmental processes
|
|
gptkbp:binds
|
dioxins
polycyclic aromatic hydrocarbons
|
|
gptkbp:discoveredBy
|
Allan Poland
|
|
gptkbp:discoveredIn
|
1976
|
|
gptkbp:encodes
|
aryl hydrocarbon receptor protein
|
|
gptkbp:Entrez_Gene_ID
|
196
ENSG00000106546
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:thymus
liver
spleen
|
|
gptkbp:fullName
|
Aryl hydrocarbon receptor
|
|
gptkbp:function
|
transcription factor
DNA binding
transcription regulatory region DNA binding
mediates response to environmental toxins
|
|
gptkbp:GOProcess
|
regulation of transcription, DNA-templated
response to xenobiotic stimulus
|
|
gptkbp:HGNC_ID
|
348
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AHR
|
|
gptkbp:interactsWith
|
gptkb:ARNT
gptkb:HSP90
gptkb:AIP
|
|
gptkbp:length
|
848 amino acids
|
|
gptkbp:locatedOn
|
gptkb:chromosome_7
|
|
gptkbp:modulatedBy
|
inflammation
immune response
|
|
gptkbp:molecularWeight
|
96 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
autoimmune diseases
|
|
gptkbp:OMIM
|
601130
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
5NJ8
|
|
gptkbp:phosphorylates
|
Ser36
|
|
gptkbp:proteinFamily
|
basic helix-loop-helix PAS family
|
|
gptkbp:regulates
|
CYP1A1
CYP1B1
xenobiotic-metabolizing enzymes
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
P35869
|
|
gptkbp:bfsParent
|
gptkb:aryl_hydrocarbon_receptor_(AhR)
|
|
gptkbp:bfsLayer
|
6
|