Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic alteration
|
| gptkbp:associatedWith |
gptkb:anaplastic_large_cell_lymphoma
gptkb:non-small_cell_lung_cancer |
| gptkbp:cause |
constitutive kinase activation
|
| gptkbp:common_fusion_partner |
gptkb:EML4
gptkb:TPM3 gptkb:NPM1 |
| gptkbp:detects |
gptkb:FISH
gptkb:RT-PCR immunohistochemistry |
| gptkbp:firstDescribed |
1994
|
| https://www.w3.org/2000/01/rdf-schema#label |
ALK rearrangement
|
| gptkbp:involvedIn |
gptkb:ALK
|
| gptkbp:locatedOnChromosome |
2p23
|
| gptkbp:result |
gptkb:protein
|
| gptkbp:targetOfDrug |
gptkb:alectinib
gptkb:brigatinib gptkb:ceritinib gptkb:crizotinib gptkb:lorlatinib |
| gptkbp:bfsParent |
gptkb:cancer
|
| gptkbp:bfsLayer |
4
|