Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
TSR-I
ActRIB Activin A receptor type 1B SKR2 |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:fibrodysplasia_ossificans_progressiva |
| gptkbp:discoveredBy |
Massagué J et al.
|
| gptkbp:encodedBy |
ACVR1B gene
|
| gptkbp:enzymeClassification |
EC 2.7.11.30
|
| gptkbp:formsComplexWith |
type II activin receptors
|
| gptkbp:fullName |
Activin receptor-like kinase 4
|
| gptkbp:function |
serine/threonine kinase receptor
type I receptor for activin and related ligands |
| gptkbp:gene |
ACVR1B
|
| https://www.w3.org/2000/01/rdf-schema#label |
ALK4
|
| gptkbp:ligand |
activin A
nodal |
| gptkbp:locatedOnChromosome |
12q13
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:molecularWeight |
57 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:pathway |
gptkb:TGF-beta_signaling_pathway
|
| gptkbp:phosphorylates |
gptkb:SMAD2
gptkb:SMAD3 |
| gptkbp:UniProtID |
P36896
|
| gptkbp:bfsParent |
gptkb:Nodal_gene
|
| gptkbp:bfsLayer |
7
|