|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:PKB_gamma
gptkb:RAC-gamma_serine/threonine-protein_kinase
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
cell proliferation
cell survival
|
|
gptkbp:encodes
|
AKT3 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000117020
10000
|
|
gptkbp:expressedIn
|
gptkb:placenta
gptkb:testis
brain
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:391
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AKT3 gene
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
1q44
|
|
gptkbp:memberOf
|
gptkb:AKT_gene_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:megalencephaly-polymicrogyria-polydactyly-hydrocephalus_syndrome
|
|
gptkbp:OMIM
|
611223
|
|
gptkbp:orthologInMouse
|
gptkb:Akt3
|
|
gptkbp:pathway
|
gptkb:mTOR_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:proteinKinaseActivity
|
serine/threonine kinase
|
|
gptkbp:regulates
|
apoptosis
metabolism
cell growth
|
|
gptkbp:UniProtID
|
Q9Y243
|
|
gptkbp:bfsParent
|
gptkb:Akt_kinase
gptkb:megalencephaly-polymicrogyria-polydactyly-hydrocephalus_syndrome_(MPPH)
|
|
gptkbp:bfsLayer
|
7
|