gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
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gptkbp:alternativeName
|
gptkb:β1-adrenergic_receptor
Beta-1 adrenoceptor
|
gptkbp:biologicalProcess
|
regulation of heart rate
regulation of cardiac muscle contraction
adrenergic receptor activity
|
gptkbp:drugClass
|
adrenergic receptor
|
gptkbp:encodedBy
|
gptkb:ADRB1_gene
|
gptkbp:Entrez_Gene_ID
|
153
|
gptkbp:expressedIn
|
gptkb:kidney
heart
adipose tissue
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
gptkbp:fullName
|
gptkb:Beta-1_adrenergic_receptor
|
gptkbp:function
|
gptkb:G_protein-coupled_receptor
mediates effects of adrenaline and noradrenaline
|
gptkbp:HGNC_ID
|
gptkb:HGNC:270
|
https://www.w3.org/2000/01/rdf-schema#label
|
ADRβ1
|
gptkbp:interactsWith
|
gptkb:GNB1
gptkb:GNAS
|
gptkbp:locatedOnChromosome
|
10q25.3
|
gptkbp:location
|
gptkb:cell_membrane
|
gptkbp:mutationAssociatedWith
|
heart failure
hypertension
|
gptkbp:OMIM
|
109630
|
gptkbp:structureType
|
7-transmembrane domain protein
|
gptkbp:target
|
beta-blockers
|
gptkbp:UniProtID
|
P08588
|
gptkbp:bfsParent
|
gptkb:Beta-1_adrenergic_receptor
|
gptkbp:bfsLayer
|
7
|