Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:chronic_myeloid_leukemia
gptkb:Oncology |
| gptkbp:form |
p190
p210 p230 |
| gptkbp:function |
tyrosine kinase
|
| gptkbp:has_role |
gptkb:Oni
DNA repair cell cycle regulation cell differentiation signal transduction tumorigenesis cell adhesion cell migration response to infection response to inflammation response to stress response to immunotherapy response to DNA damage response to cytokines response to growth factors response to hormones response to hypoxia response to ionizing radiation response to mechanical stress response to oxidative stress response to chemotherapeutic agents response to extracellular matrix response to metabolic stress response to targeted therapies |
| gptkbp:has_website |
SH2 domain
SH3 domain kinase domain |
| https://www.w3.org/2000/01/rdf-schema#label |
ABL1 protein
|
| gptkbp:initiated_by |
gptkb:imatinib
gptkb:dasatinib gptkb:nilotinib |
| gptkbp:interacts_with |
BCR protein
|
| gptkbp:involved_in |
apoptosis regulation
cell proliferation cell signaling |
| gptkbp:is_expressed_in |
gptkb:Brain
muscle cells hematopoietic cells |
| gptkbp:is_regulated_by |
phosphorylation
ubiquitination acetylation |
| gptkbp:located_in |
gptkb:Atom
|
| gptkbp:produced_by |
gptkb:Anthropology
|
| gptkbp:promoter |
gptkb:ABL1
|
| gptkbp:weight |
approximately 145 k Da
|
| gptkbp:bfsParent |
gptkb:ABL1_gene
|
| gptkbp:bfsLayer |
8
|