Statements (18)
Predicate | Object |
---|---|
gptkbp:instanceOf |
protein structural motif
|
gptkbp:discoveredIn |
Ras GTPase studies
|
gptkbp:firstDescribed |
Almira Hoog and John Kuriyan
|
gptkbp:foundIn |
gptkb:GTPase_proteins
gptkb:ATPase_proteins |
gptkbp:function |
catalyzes hydrolysis of nucleoside triphosphates
|
https://www.w3.org/2000/01/rdf-schema#label |
arginine finger
|
gptkbp:interactsWith |
phosphate group of nucleotide
|
gptkbp:mechanismOfAction |
provides positive charge for catalysis
stabilizes transition state |
gptkbp:mutationAssociatedWith |
loss of catalytic activity
|
gptkbp:presentIn |
gptkb:RecA_family_proteins
AAA+ ATPases Ras family GTPases |
gptkbp:requires |
ATP hydrolysis
GTP hydrolysis |
gptkbp:bfsParent |
gptkb:AAA_(protein_family)
|
gptkbp:bfsLayer |
6
|