|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:activatedBy
|
gptkb:Gs_protein
|
|
gptkbp:alternativeName
|
gptkb:A2A_adenosine_receptor
gptkb:ADORA2A
A2AR
|
|
gptkbp:binds
|
gptkb:adenosine
|
|
gptkbp:encodedBy
|
ADORA2A gene
|
|
gptkbp:enemyOf
|
gptkb:regadenoson
gptkb:ZM241385
gptkb:adenosine
caffeine
istradefylline
CGS21680
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ADORA2A
|
|
gptkbp:expressedIn
|
brain
heart
immune cells
|
|
gptkbp:formsHeterodimerWith
|
D2 dopamine receptor
|
|
gptkbp:foundIn
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:hasClinicalUse
|
treatment of Parkinson's disease
diagnosis of myocardial perfusion
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Adenosine A2A receptor
|
|
gptkbp:improves
|
cAMP production
|
|
gptkbp:involvedIn
|
immune response
neurotransmission
regulation of blood flow
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
22q11.23
|
|
gptkbp:modulatedBy
|
dopaminergic signaling
|
|
gptkbp:OMIM
|
102776
|
|
gptkbp:overexpressedIn
|
gptkb:striatum
|
|
gptkbp:PDB
|
3EML
|
|
gptkbp:target
|
Parkinson's disease drugs
|
|
gptkbp:UniProtID
|
P29274
|
|
gptkbp:bfsParent
|
gptkb:CHEMBL2105728
gptkb:CHEMBL1235488
|
|
gptkbp:bfsLayer
|
6
|