|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:binds
|
gptkb:adenosine
|
|
gptkbp:couplingType
|
gptkb:Gi_protein
|
|
gptkbp:encodedBy
|
ADORA1 gene
|
|
gptkbp:enemyOf
|
gptkb:CHA
gptkb:CPA
gptkb:theophylline
gptkb:DPCPX
caffeine
N6-cyclopentyladenosine
PSB36
|
|
gptkbp:Entrez_Gene_ID
|
134
|
|
gptkbp:expressedIn
|
gptkb:adipose_tissue
gptkb:cancer
gptkb:kidney
gptkb:spinal_cord
gptkb:testis
brain
heart
|
|
gptkbp:foundIn
|
gptkb:human
gptkb:mouse
gptkb:right
|
|
gptkbp:HGNC_ID
|
HGNC:262
|
|
gptkbp:inhibitedBy
|
gptkb:adenylate_cyclase
|
|
gptkbp:involvedIn
|
sedation
anticonvulsant effect
sleep regulation
analgesia
regulation of blood pressure
neuroprotection
cardioprotection
inhibition of neurotransmitter release
regulation of heart rate
modulation of synaptic transmission
negative chronotropic effect
negative dromotropic effect
negative inotropic effect
renal vasoconstriction
|
|
gptkbp:locatedOn
|
chromosome 1 (human)
|
|
gptkbp:molecularWeight
|
~36 kDa
|
|
gptkbp:OMIM
|
102776
|
|
gptkbp:regulates
|
sleep
neurotransmitter release
cardiac function
renal blood flow
|
|
gptkbp:structure
|
7 transmembrane domains
|
|
gptkbp:UniProtID
|
P30542
|
|
gptkbp:bfsParent
|
gptkb:adenosine_receptor
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
A1 adenosine receptor
|