Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:binds |
gptkb:adenosine
|
| gptkbp:couplingType |
gptkb:Gi_protein
|
| gptkbp:encodedBy |
ADORA1 gene
|
| gptkbp:enemyOf |
gptkb:CHA
gptkb:CPA gptkb:theophylline gptkb:DPCPX caffeine N6-cyclopentyladenosine PSB36 |
| gptkbp:Entrez_Gene_ID |
134
|
| gptkbp:expressedIn |
gptkb:cancer
gptkb:kidney gptkb:spinal_cord gptkb:testis brain heart adipose tissue |
| gptkbp:foundIn |
gptkb:human
gptkb:mouse right |
| gptkbp:HGNC_ID |
HGNC:262
|
| https://www.w3.org/2000/01/rdf-schema#label |
A1 adenosine receptor
|
| gptkbp:inhibitedBy |
gptkb:adenylate_cyclase
|
| gptkbp:involvedIn |
sedation
anticonvulsant effect sleep regulation analgesia regulation of blood pressure neuroprotection cardioprotection inhibition of neurotransmitter release regulation of heart rate modulation of synaptic transmission negative chronotropic effect negative dromotropic effect negative inotropic effect renal vasoconstriction |
| gptkbp:locatedOn |
chromosome 1 (human)
|
| gptkbp:molecularWeight |
~36 kDa
|
| gptkbp:OMIM |
102776
|
| gptkbp:regulates |
sleep
neurotransmitter release cardiac function renal blood flow |
| gptkbp:structure |
7 transmembrane domains
|
| gptkbp:UniProtID |
P30542
|
| gptkbp:bfsParent |
gptkb:adenosine_receptor
|
| gptkbp:bfsLayer |
6
|