Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
dopamine biosynthesis
|
| gptkbp:encodes |
gptkb:tyrosine_hydroxylase
|
| gptkbp:Entrez_Gene_ID |
7054
ENSG00000180176 |
| gptkbp:expressedIn |
gptkb:adrenal_medulla
central nervous system |
| gptkbp:function |
catalyzes conversion of L-tyrosine to L-DOPA
|
| https://www.w3.org/2000/01/rdf-schema#label |
tyrosine hydroxylase gene
|
| gptkbp:locatedOnChromosome |
chromosome 11
|
| gptkbp:mutationAssociatedWith |
gptkb:Parkinson's_disease
dopa-responsive dystonia |
| gptkbp:OMIM |
191290
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Th
|
| gptkbp:product |
tyrosine 3-monooxygenase
|
| gptkbp:regulates |
regulated by phosphorylation
regulated by feedback inhibition |
| gptkbp:symbol |
TH
|
| gptkbp:UniProtID |
P07101
|
| gptkbp:bfsParent |
gptkb:CREB
|
| gptkbp:bfsLayer |
7
|