Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:TDO
gptkb:tryptophan_2,3-dioxygenase |
| gptkbp:biologicalProcess |
dioxygenase activity
|
| gptkbp:catalyzes |
oxidation of tryptophan to N-formylkynurenine
|
| gptkbp:cofactor |
hemoglobin
|
| gptkbp:EC_number |
1.13.11.11
|
| gptkbp:foundIn |
liver
|
| gptkbp:gene |
gptkb:TDO2
|
| gptkbp:GO_term |
GO:0004833
|
| https://www.w3.org/2000/01/rdf-schema#label |
tryptophan pyrrolase
|
| gptkbp:inhibitedBy |
inhibited by 1-methyltryptophan
inhibited by allopurinol |
| gptkbp:organism |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:pathway |
kynurenine pathway
|
| gptkbp:product |
N-formylkynurenine
|
| gptkbp:regulates |
induced by glucocorticoids
regulated by tryptophan levels |
| gptkbp:substrate |
L-tryptophan
|
| gptkbp:UniProtID |
P48775
|
| gptkbp:bfsParent |
gptkb:Tryptophan_2,3-dioxygenase
|
| gptkbp:bfsLayer |
6
|