ticlopidine

GPTKB entity

Statements (43)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkb:anticoagulant
thienopyridine
gptkbp:approvedBy 1989
gptkbp:ATCCode B01AC05
gptkbp:brand Ticlid
gptkbp:CASNumber 55142-85-3
gptkbp:category gptkb:pyridines
antiplatelet drug
thioethers
gptkbp:contraindication active bleeding
severe liver disease
gptkbp:discoveredBy gptkb:Sanofi
gptkbp:eliminationHalfLife 12 hours
gptkbp:hasInChIKey YGBMUTUPAWYKAY-UHFFFAOYSA-N
gptkbp:hasMolecularFormula C14H14ClNS
gptkbp:hasSMILES Clc1ccc(cc1)C2=NC(CS2)(C)C
https://www.w3.org/2000/01/rdf-schema#label ticlopidine
gptkbp:KEGGID D02341
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction ADP receptor inhibitor
gptkbp:MeSH_ID D016692
gptkbp:metabolism liver
gptkbp:molecularWeight 263.79 g/mol
gptkbp:pregnancyCategory B (US)
gptkbp:PubChem_CID gptkb:CHEMBL1082
5437
5239
DB00208
gptkbp:replacedBy gptkb:clopidogrel
gptkbp:routeOfAdministration oral
gptkbp:sideEffect diarrhea
rash
neutropenia
thrombotic thrombocytopenic purpura
liver dysfunction
gptkbp:UNII OMJ7L0G7LC
gptkbp:usedFor prevention of stroke
prevention of thrombotic events
gptkbp:bfsParent gptkb:CYP3A5
gptkb:prasugrel
gptkb:CYP2B6
gptkbp:bfsLayer 6