|
gptkbp:instanceOf
|
gptkb:antibiotic
ketolide
|
|
gptkbp:approvedBy
|
gptkb:FDA
2004
|
|
gptkbp:ATCCode
|
J01FA15
|
|
gptkbp:blackBoxWarning
|
yes
|
|
gptkbp:brand
|
Ketek
|
|
gptkbp:CASNumber
|
191114-48-4
|
|
gptkbp:chemicalFormula
|
C43H65N5O10
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
|
|
gptkbp:discoveredBy
|
gptkb:Sanofi-Aventis
|
|
gptkbp:eliminationHalfLife
|
10 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
telithromycin
|
|
gptkbp:KEGGID
|
D01960
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
protein synthesis inhibitor
|
|
gptkbp:metabolism
|
gptkb:CYP3A4
|
|
gptkbp:molecularWeight
|
813.0 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201197
DB00976
158610
|
|
gptkbp:riskFactor
|
QT prolongation
hepatotoxicity
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
liver toxicity
gastrointestinal upset
visual disturbances
|
|
gptkbp:spectrumOfActivity
|
Gram-positive bacteria
some Gram-negative bacteria
atypical bacteria
|
|
gptkbp:target
|
bacterial ribosome 50S subunit
|
|
gptkbp:UNII
|
K4B6MH59X3
|
|
gptkbp:usedFor
|
community-acquired pneumonia
|
|
gptkbp:bfsParent
|
gptkb:CYP3A5
|
|
gptkbp:bfsLayer
|
6
|