Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Bastiladon
|
| gptkbp:administered_by |
oral tablet
|
| gptkbp:approves |
1950s
|
| gptkbp:atccode |
J01 EB02
|
| gptkbp:brand |
gptkb:Sulfamethoxazole
|
| gptkbp:casnumber |
57-61-8
|
| gptkbp:chemical_formula |
C12 H14 N4 O3 S
|
| gptkbp:clinical_trial |
Phase II
Phase III |
| gptkbp:composed_by |
gptkb:chemical_compound
reaction with sulfuric acid reaction with acetic anhydride reaction with formaldehyde reaction with hydrochloric acid reaction with sodium acetate reaction with sodium bicarbonate reaction with sodium bromide reaction with sodium carbonate reaction with sodium chloride reaction with sodium hydroxide reaction with sodium iodide reaction with sodium nitrite reaction with sodium phosphate reaction with sodium sulfate reaction with sodium sulfide reaction with sodium sulfite reaction with sodium thiocyanate reaction with sodium thiosulfate reaction with sulfanilamide |
| gptkbp:contraindication |
gptkb:disease
liver disease pregnancy |
| gptkbp:dissolved |
soluble in water
soluble in alcohol |
| gptkbp:dosage_form |
suspension
injection |
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
sulfamethazine
|
| gptkbp:interacts_with |
gptkb:methotrexate
gptkb:phenytoin gptkb:warfarin |
| gptkbp:mechanism_of_action |
inhibits bacterial folic acid synthesis
|
| gptkbp:metabolism |
liver
|
| gptkbp:related_to |
gptkb:sulfamethoxazole
gptkb:trimethoprim |
| gptkbp:side_effect |
headache
nausea fever rash |
| gptkbp:targets |
Gram-negative bacteria
Gram-positive bacteria |
| gptkbp:used_for |
bacterial infections
|
| gptkbp:bfsParent |
gptkb:sulfanilamide
|
| gptkbp:bfsLayer |
7
|