|
gptkbp:instance_of
|
gptkb:Bastiladon
|
|
gptkbp:approves
|
gptkb:FDA
|
|
gptkbp:availability
|
generic form available
|
|
gptkbp:brand
|
gptkb:Sulfamylon
|
|
gptkbp:casnumber
|
63-74-1
|
|
gptkbp:category
|
antimicrobial agent
|
|
gptkbp:chemical_formula
|
C6 H8 N2 O2 S
|
|
gptkbp:class
|
gptkb:pharmaceuticals
|
|
gptkbp:clinical_trial
|
ongoing for new formulations
|
|
gptkbp:composed_by
|
from aniline and sulfanilamide
|
|
gptkbp:contraindication
|
pregnancy
|
|
gptkbp:development
|
by Bayer AG
|
|
gptkbp:discovered_by
|
gptkb:1932
|
|
gptkbp:discovery
|
by Gerhard Domagk
|
|
gptkbp:dissolved
|
soluble in water
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:first_introduced
|
treatment of streptococcal infections
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
sulfanilamide
|
|
gptkbp:impact
|
reduced mortality from infections
|
|
gptkbp:interacts_with
|
gptkb:warfarin
|
|
gptkbp:invention
|
expired
|
|
gptkbp:lifespan
|
6 to 12 hours
|
|
gptkbp:marketed_as
|
gptkb:Prontosil
|
|
gptkbp:mechanism_of_action
|
inhibits bacterial folic acid synthesis
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:notable_work
|
used in World War II
|
|
gptkbp:packaging
|
tablets and liquid form
|
|
gptkbp:pharmacokinetics
|
absorbed in the gastrointestinal tract
|
|
gptkbp:related_products
|
gptkb:sulfadiazine
gptkb:sulfamethazine
gptkb:sulfisoxazole
gptkb:sulfamethoxazole
|
|
gptkbp:related_to
|
sulfanilamide antibiotics
|
|
gptkbp:research_areas
|
antibiotic resistance
|
|
gptkbp:route_of_administration
|
oral
|
|
gptkbp:safety
|
monitor for allergic reactions
generally safe when used as directed
|
|
gptkbp:side_effect
|
dizziness
headache
nausea
allergic reactions
vomiting
diarrhea
|
|
gptkbp:storage
|
store at room temperature
|
|
gptkbp:structure
|
sulfonamide group
|
|
gptkbp:treatment
|
urinary tract infections
|
|
gptkbp:used_for
|
bacterial infections
|
|
gptkbp:weight
|
172.21 g/mol
|
|
gptkbp:bfsParent
|
gptkb:Gerhard_Domagk
|
|
gptkbp:bfsLayer
|
6
|