two-pore-domain potassium channel
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
K2P channel
leak potassium channel |
| gptkbp:discoveredIn |
1996
|
| gptkbp:encodedBy |
KCNK genes
|
| gptkbp:family |
TALK-1
TASK-1 THIK-1 TREK-1 TWIK-1 |
| gptkbp:foundIn |
gptkb:cell_membrane
|
| gptkbp:function |
maintain resting membrane potential
regulate neuronal excitability |
| https://www.w3.org/2000/01/rdf-schema#label |
two-pore-domain potassium channel
|
| gptkbp:modulatedBy |
gptkb:temperature
lipids pH volatile anesthetics mechanical stretch |
| gptkbp:OMIM |
602215
|
| gptkbp:permeableTo |
selective for potassium ions
|
| gptkbp:presentIn |
animals
humans mammals |
| gptkbp:proteinFamily |
gptkb:KCNK
|
| gptkbp:relatedTo |
gptkb:cell_membrane
ion channel potassium channel |
| gptkbp:structure |
contains two pore-forming domains per subunit
|
| gptkbp:subunit |
dimeric
|
| gptkbp:UniProtID |
Q9NYG8 (for KCNK1/TWIK-1)
|
| gptkbp:bfsParent |
gptkb:potassium_channels
|
| gptkbp:bfsLayer |
7
|