Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
ion channel
|
| gptkbp:activatedBy |
changes in membrane potential
|
| gptkbp:composedOf |
protein subunits
|
| gptkbp:discoveredBy |
gptkb:Bernard_Katz
|
| gptkbp:dysregulationAssociatedWith |
gptkb:arrhythmia
epilepsy periodic paralysis |
| gptkbp:encodedBy |
various genes
|
| gptkbp:foundIn |
gptkb:cell_membrane
|
| gptkbp:function |
regulate ion flow
|
| https://www.w3.org/2000/01/rdf-schema#label |
voltage-gated ion channel
|
| gptkbp:importantFor |
muscle contraction
neuronal signaling action potential |
| gptkbp:permitsPassageOf |
chloride ions
calcium ions potassium ions sodium ions |
| gptkbp:regulates |
phosphorylation
auxiliary subunits |
| gptkbp:structure |
pore domain
transmembrane domains voltage-sensing domain |
| gptkbp:studiedIn |
neuroscience
|
| gptkbp:subspecies |
gptkb:voltage-gated_potassium_channel
voltage-gated calcium channel voltage-gated chloride channel |
| gptkbp:target |
anticonvulsants
antiarrhythmic drugs local anesthetics |
| gptkbp:bfsParent |
gptkb:potassium_channels
|
| gptkbp:bfsLayer |
7
|