phosphoprotein phosphatase 1
GPTKB entity
Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
PP1
|
| gptkbp:biologicalProcess |
protein serine/threonine phosphatase activity
|
| gptkbp:catalyzes |
dephosphorylation of serine/threonine residues
|
| gptkbp:conservedIn |
gptkb:yeast
invertebrates mammals plants |
| gptkbp:encodedBy |
gptkb:PPP1CA
gptkb:PPP1CB gptkb:PPP1CC |
| gptkbp:enzymeCommissionNumber |
3.1.3.16
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:GO_term |
gptkb:GO:0006470_(protein_dephosphorylation)
GO:0005737 (cytoplasm) GO:0005634 (nucleus) GO:0005829 (cytosol) GO:0005654 (nucleoplasm) GO:0004722 (protein serine/threonine phosphatase activity) |
| gptkbp:hasIsoform |
PP1α
PP1β PP1γ |
| https://www.w3.org/2000/01/rdf-schema#label |
phosphoprotein phosphatase 1
|
| gptkbp:involvedIn |
gptkb:synaptic_plasticity
apoptosis signal transduction cell cycle regulation metabolic pathways transcription regulation |
| gptkbp:molecularWeight |
~37 kDa
|
| gptkbp:partOf |
protein phosphatase 1 complex
|
| gptkbp:regulates |
cell division
protein synthesis muscle contraction glycogen metabolism neuronal signaling |
| gptkbp:requires |
cell viability
|
| gptkbp:subunit |
catalytic subunit
regulatory subunit |
| gptkbp:target |
gptkb:microcystin-LR
gptkb:okadaic_acid DARPP-32 calyculin A inhibitor-2 nuclear inhibitor of PP1 (NIPP1) protein phosphatase inhibitor-1 tautomycin |
| gptkbp:bfsParent |
gptkb:Glycogen_phosphorylase
|
| gptkbp:bfsLayer |
7
|