|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:activatedBy
|
gptkb:AMP
phosphorylase kinase
adrenaline (indirectly via signaling)
glucagon (indirectly via signaling)
|
|
gptkbp:allosteric_site
|
AMP binding site
glucose binding site
ATP binding site
glucose-6-phosphate binding site
|
|
gptkbp:associatedWith
|
gptkb:Hers_disease
gptkb:McArdle_disease
|
|
gptkbp:catalyzes
|
glycogen breakdown
|
|
gptkbp:cofactor
|
gptkb:pyridoxal_phosphate
|
|
gptkbp:discoveredBy
|
gptkb:Carl_Ferdinand_Cori
gptkb:Gerty_Cori
|
|
gptkbp:EC_number
|
2.4.1.1
|
|
gptkbp:enzymeClassification
|
gptkb:glycosyltransferase
|
|
gptkbp:form
|
phosphorylase a
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
liver
|
|
gptkbp:gene
|
gptkb:PYGB
gptkb:PYGL
gptkb:PYGM
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Glycogen phosphorylase
|
|
gptkbp:inactive_form
|
phosphorylase b
|
|
gptkbp:inhibitedBy
|
gptkb:ATP
gptkb:glucose-6-phosphate
gptkb:phosphoprotein_phosphatase_1
caffeine
glucose
glucose analogs
|
|
gptkbp:locale
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
~97 kDa (dimer)
|
|
gptkbp:Nobel_Prize_related
|
gptkb:1947_Nobel_Prize_in_Physiology_or_Medicine
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
glycogenolysis
|
|
gptkbp:PDB
|
1GPB
|
|
gptkbp:phosphorylates
|
Ser14
|
|
gptkbp:product
|
glucose-1-phosphate
shortened glycogen
|
|
gptkbp:proteinFamily
|
gptkb:glycogen_phosphorylase_family
|
|
gptkbp:regulates
|
phosphorylation
allosteric effectors
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:glycogen
inorganic phosphate
|
|
gptkbp:subunit
|
alpha subunit
beta subunit
gamma subunit
|
|
gptkbp:type
|
phosphorolysis
|
|
gptkbp:bfsParent
|
gptkb:Enzymes
|
|
gptkbp:bfsLayer
|
6
|