|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Noonan_syndrome-like_disorder
intellectual disability
|
|
gptkbp:cofactor
|
iron
manganese
|
|
gptkbp:encodes
|
serine/threonine-protein phosphatase PP1-beta catalytic subunit
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000138032
5500
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
protein phosphatase activity
dephosphorylation of serine/threonine residues
|
|
gptkbp:gene
|
gptkb:PPP1CB
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasParalog
|
gptkb:PPP1CA
gptkb:PPP1CC
|
|
gptkbp:HGNC_ID
|
9280
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PPP1CB
|
|
gptkbp:interactsWith
|
gptkb:PPP1R12A
gptkb:PPP1R2
gptkb:PPP1R3A
gptkb:PPP1R3B
gptkb:PPP1R3C
gptkb:PPP1R7
gptkb:PPP1R8
gptkb:PPP1R9B
gptkb:PPP1R15A
PPP1R12B
PPP1R12C
PPP1R9A
|
|
gptkbp:involvedIn
|
cell division
protein synthesis
glycogen metabolism
muscle contractility
neuronal signaling
|
|
gptkbp:locatedOnChromosome
|
gptkb:2p23.2
chromosome 2
|
|
gptkbp:molecularWeight
|
37 kDa
|
|
gptkbp:numberOfExons
|
8
|
|
gptkbp:OMIM
|
600590
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Ppp1cb
|
|
gptkbp:PDB
|
1S70
|
|
gptkbp:proteinFamily
|
PPP phosphatase family
|
|
gptkbp:RefSeq
|
NM_002709
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
mitochondrion
|
|
gptkbp:UniProtID
|
gptkb:P62140
|
|
gptkbp:bfsParent
|
gptkb:PPP1R12A
|
|
gptkbp:bfsLayer
|
7
|