Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:PLCE1
NPHS3 phospholipase C-epsilon-1 |
| gptkbp:associatedWith |
nephrotic syndrome
esophageal squamous cell carcinoma |
| gptkbp:domain |
gptkb:PH_domain
gptkb:EF-hand_domain C2 domain CDC25 homology domain Ras-associating domain |
| gptkbp:enzymeCommissionNumber |
EC 3.1.4.11
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
hydrolyzes phosphatidylinositol 4,5-bisphosphate
generates second messengers diacylglycerol and inositol trisphosphate |
| gptkbp:gene |
gptkb:PLCE1
|
| https://www.w3.org/2000/01/rdf-schema#label |
phospholipase C, epsilon 1
|
| gptkbp:interactsWith |
gptkb:Rap_proteins
gptkb:Ras_proteins |
| gptkbp:locatedOnChromosome |
10q23.33
|
| gptkbp:molecularWeight |
~230 kDa
|
| gptkbp:subcellularLocation |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:UniProtID |
Q9P212
|
| gptkbp:bfsParent |
gptkb:PLCE1
|
| gptkbp:bfsLayer |
7
|