Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
gptkb:PDE3
|
| gptkbp:EC_number |
3.1.4.17
|
| gptkbp:expressedIn |
heart
adipose tissue vascular smooth muscle |
| gptkbp:family |
phosphodiesterase family
|
| gptkbp:function |
hydrolyzes cAMP
hydrolyzes cGMP |
| gptkbp:gene |
PDE3A
PDE3B |
| https://www.w3.org/2000/01/rdf-schema#label |
phosphodiesterase type 3
|
| gptkbp:inhibitedBy |
gptkb:milrinone
gptkb:amrinone cilostazol |
| gptkbp:location |
gptkb:cell_membrane
gptkb:cytoplasm |
| gptkbp:medicalUse |
heart failure treatment
intermittent claudication treatment |
| gptkbp:regulates |
cardiac contractility
vascular smooth muscle relaxation |
| gptkbp:bfsParent |
gptkb:Phosphodiesterase
|
| gptkbp:bfsLayer |
7
|