Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
phosphodiesterase inhibitor |
gptkbp:ATCCode |
C01CE01
|
gptkbp:CASNumber |
60719-84-8
|
gptkbp:contraindication |
severe aortic or pulmonic valvular disease
|
gptkbp:decreasedIn |
systemic vascular resistance
|
gptkbp:discoveredIn |
1978
|
gptkbp:eliminationHalfLife |
5-8 hours
|
gptkbp:excretion |
renal
|
gptkbp:hasMolecularFormula |
C10H9N3O
|
https://www.w3.org/2000/01/rdf-schema#label |
amrinone
|
gptkbp:improves |
cardiac output
cardiac contractility |
gptkbp:mechanismOfAction |
inhibits phosphodiesterase III
|
gptkbp:metabolism |
hepatic
|
gptkbp:routeOfAdministration |
intravenous
|
gptkbp:sideEffect |
gptkb:arrhythmia
thrombocytopenia liver enzyme elevation |
gptkbp:synonym |
inamrinone
|
gptkbp:usedFor |
heart failure
|
gptkbp:bfsParent |
gptkb:C01CA24
|
gptkbp:bfsLayer |
7
|