milrinone

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf vasodilator
inotrope
phosphodiesterase 3 inhibitor
gptkbp:approvedBy 1980s
gptkbp:ATCCode C01CE02
gptkbp:CASNumber 78415-72-2
gptkbp:discoveredBy gptkb:Winthrop_Laboratories
gptkbp:effect increases cardiac contractility
decreases afterload
gptkbp:eliminationHalfLife 2.3 hours
gptkbp:excretion renal
gptkbp:hasMolecularFormula C12H9N3O
https://www.w3.org/2000/01/rdf-schema#label milrinone
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction increases cAMP by inhibiting phosphodiesterase 3
gptkbp:metabolism minimal hepatic metabolism
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect gptkb:arrhythmia
hypotension
thrombocytopenia
gptkbp:synonym Primacor
gptkbp:usedFor heart failure
cardiogenic shock
gptkbp:bfsParent gptkb:Cyclic_Phosphodiesterase
gptkbp:bfsLayer 6