phosphatidylinositol 3-kinase complex
GPTKB entity
Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activity |
kinase activity
|
| gptkbp:alternativeName |
gptkb:phosphoinositide_3-kinase_complex
gptkb:PI3K_complex |
| gptkbp:component |
gptkb:PI3K/AKT_signaling_pathway
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
phosphorylation of phosphatidylinositol lipids
|
| https://www.w3.org/2000/01/rdf-schema#label |
phosphatidylinositol 3-kinase complex
|
| gptkbp:involvedIn |
cell proliferation
cell survival metabolism cancer progression cell growth |
| gptkbp:regulates |
gptkb:AKT
gptkb:mTOR |
| gptkbp:subunit |
p110 catalytic subunit
p85 regulatory subunit |
| gptkbp:target |
PI3K inhibitors
|
| gptkbp:bfsParent |
gptkb:phosphoinositide_3-kinase_complex
|
| gptkbp:bfsLayer |
6
|