pediatric acute lymphoblastic leukemia

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkb:disease
gptkbp:abbreviation pediatric ALL
gptkbp:affects children
gptkbp:diagnosedBy blood test
bone marrow biopsy
gptkbp:firstDescribed early 20th century
https://www.w3.org/2000/01/rdf-schema#label pediatric acute lymphoblastic leukemia
gptkbp:ICD-10_code gptkb:C91.0
gptkbp:incidence most common childhood cancer
gptkbp:mortalityRate less than 10% with modern therapy
gptkbp:peakIncidenceAge 2-5 years
gptkbp:primarySite blood
bone marrow
gptkbp:prognosis generally favorable with treatment
gptkbp:relapse possible
gptkbp:riskFactor gptkb:Down_syndrome
genetic predisposition
previous chemotherapy
gptkbp:subclassOf leukemia
gptkbp:subspecies gptkb:B-cell_ALL
gptkb:T-cell_ALL
gptkbp:symptom fever
fatigue
easy bruising
frequent infections
gptkbp:treatment radiation therapy
chemotherapy
stem cell transplant
gptkbp:bfsParent gptkb:CAR-T_therapy
gptkbp:bfsLayer 7