Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:discoveredBy |
gptkb:Arnold_Levine
gptkb:David_Lane |
| gptkbp:domain |
DNA-binding domain
oligomerization domain transactivation domain |
| gptkbp:evolvesFrom |
gptkb:metazoans
|
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
tumor suppression
|
| gptkbp:gene |
gptkb:TP53
gptkb:TP73 gptkb:TP63 |
| gptkbp:hasMember |
gptkb:p63
gptkb:p73 gptkb:p53 |
| gptkbp:hasParalog |
gptkb:p63
gptkb:p73 |
| https://www.w3.org/2000/01/rdf-schema#label |
p53 protein family
|
| gptkbp:includes |
gptkb:p63
gptkb:p73 gptkb:p53 |
| gptkbp:mutationAssociatedWith |
gptkb:Li-Fraumeni_syndrome
various cancers |
| gptkbp:regulates |
apoptosis
cell differentiation DNA repair cell cycle senescence genomic stability |
| gptkbp:relatedTo |
gptkb:cancer
|
| gptkbp:bfsParent |
gptkb:p63
|
| gptkbp:bfsLayer |
6
|