Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:controls |
gptkb:G1/S_transition
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
|
| gptkbp:gene |
gptkb:CDKN2A
|
| https://www.w3.org/2000/01/rdf-schema#label |
p16INK4a-CDK4 pathway
|
| gptkbp:inhibitedBy |
CDK4 activity
|
| gptkbp:involvesProtein |
gptkb:p16INK4a
gptkb:CDK4 |
| gptkbp:mutationAssociatedWith |
uncontrolled cell proliferation
|
| gptkbp:prevention |
phosphorylation of RB protein
|
| gptkbp:regulates |
cell cycle
|
| gptkbp:regulatesPhase |
G1 phase
|
| gptkbp:relatedTo |
gptkb:RB_pathway
|
| gptkbp:studiedIn |
oncology
|
| gptkbp:target |
oncogenic mutations
|
| gptkbp:tumorSuppressorRole |
gptkb:p16INK4a
|
| gptkbp:bfsParent |
gptkb:HGNC:1784
|
| gptkbp:bfsLayer |
7
|