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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alsoKnownAs
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gptkb:PIK3R1
phosphoinositide-3-kinase regulatory subunit alpha
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gptkbp:encodedBy
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PIK3R1 gene
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000145675
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gptkbp:function
|
regulatory subunit of phosphoinositide 3-kinase (PI3K)
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gptkbp:gene
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gptkb:PIK3R1
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gptkbp:interactsWith
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gptkb:IRS1
SH2 domain-containing proteins
p110 catalytic subunit of PI3K
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gptkbp:involvedIn
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gptkb:PI3K/AKT_signaling_pathway
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gptkbp:locale
|
gptkb:cytoplasm
gptkb:plasma_membrane
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gptkbp:locatedOnChromosome
|
chromosome 5q13.1
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gptkbp:molecularWeight
|
85-120 kDa
|
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gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:immunodeficiency
SHORT syndrome
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:RefSeq
|
NP_852664
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gptkbp:regulates
|
cell survival
metabolism
cell growth
PI3K catalytic activity
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gptkbp:structure
|
contains SH2 domains
contains SH3 domain
|
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gptkbp:UniProtID
|
gptkb:P27986
|
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gptkbp:bfsParent
|
gptkb:phosphoinositide-3-kinase,_catalytic,_gamma_polypeptide
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gptkbp:bfsLayer
|
7
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https://www.w3.org/2000/01/rdf-schema#label
|
p120-PI3K
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