|
gptkbp:instanceOf
|
gptkb:drug
proton pump inhibitor
|
|
gptkbp:approvedBy
|
1988
|
|
gptkbp:ATCCode
|
A02BC01
|
|
gptkbp:bioavailability
|
30–40% (oral)
|
|
gptkbp:brand
|
gptkb:Losec
gptkb:Prilosec
|
|
gptkbp:CASNumber
|
73590-58-6
|
|
gptkbp:contraindication
|
hypersensitivity to omeprazole
|
|
gptkbp:developedBy
|
gptkb:Sweden
|
|
gptkbp:discoveredBy
|
gptkb:Astra_AB
|
|
gptkbp:eliminationHalfLife
|
0.5–1 hour
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:hasEnantiomer
|
esomeprazole
|
|
gptkbp:hasMolecularFormula
|
C17H19N3O3S
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
omeprazolum
|
|
gptkbp:interactsWith
|
gptkb:warfarin
gptkb:clopidogrel
gptkb:diazepam
|
|
gptkbp:KEGGID
|
D00428
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
gptkb:Sweden
|
|
gptkbp:mechanismOfAction
|
inhibits H+/K+ ATPase
|
|
gptkbp:MeSH_ID
|
D015242
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:proteinBinding
|
95%
|
|
gptkbp:PubChem_CID
|
4594
CHEMBL127
DB00338
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
abdominal pain
headache
|
|
gptkbp:UNII
|
0A5MM307FC
|
|
gptkbp:usedFor
|
gptkb:Zollinger-Ellison_syndrome
gptkb:gastroesophageal_reflux_disease
peptic ulcer
|
|
gptkbp:bfsParent
|
gptkb:omeprazole
|
|
gptkbp:bfsLayer
|
6
|