Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
gptkbp:alternativeName |
gptkb:NSE
gptkb:gamma-enolase |
gptkbp:catalyzes |
conversion of 2-phosphoglycerate to phosphoenolpyruvate
|
gptkbp:diagnosedBy |
gptkb:neuroblastoma
Small Cell Lung Cancer other neuroendocrine tumors |
gptkbp:discoveredIn |
1970s
|
gptkbp:EC_number |
4.2.1.11
|
gptkbp:elevatedIn |
cerebrospinal fluid after neuronal injury
|
gptkbp:encodedBy |
ENO2 gene
|
gptkbp:expressedIn |
central nervous system
peripheral nervous system |
gptkbp:foundIn |
neurons
neuroendocrine cells |
gptkbp:function |
glycolytic enzyme
|
https://www.w3.org/2000/01/rdf-schema#label |
neuron-specific enolase
|
gptkbp:locatedOnChromosome |
chromosome 12q13.3
|
gptkbp:molecularWeight |
78 kDa
|
gptkbp:structure |
dimer
|
gptkbp:subunit |
gamma-gamma homodimer
|
gptkbp:UniProtID |
P09104
|
gptkbp:usedAs |
biomarker
marker for neuronal damage |
gptkbp:usedIn |
immunohistochemistry
serum biomarker tests |
gptkbp:bfsParent |
gptkb:pancreatic_neuroendocrine_tumors
|
gptkbp:bfsLayer |
6
|