neuron-specific enolase

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:NSE
gptkb:gamma-enolase
gptkbp:catalyzes conversion of 2-phosphoglycerate to phosphoenolpyruvate
gptkbp:diagnosedBy gptkb:neuroblastoma
Small Cell Lung Cancer
other neuroendocrine tumors
gptkbp:discoveredIn 1970s
gptkbp:EC_number 4.2.1.11
gptkbp:elevatedIn cerebrospinal fluid after neuronal injury
gptkbp:encodedBy ENO2 gene
gptkbp:expressedIn central nervous system
peripheral nervous system
gptkbp:foundIn neurons
neuroendocrine cells
gptkbp:function glycolytic enzyme
https://www.w3.org/2000/01/rdf-schema#label neuron-specific enolase
gptkbp:locatedOnChromosome chromosome 12q13.3
gptkbp:molecularWeight 78 kDa
gptkbp:structure dimer
gptkbp:subunit gamma-gamma homodimer
gptkbp:UniProtID P09104
gptkbp:usedAs biomarker
marker for neuronal damage
gptkbp:usedIn immunohistochemistry
serum biomarker tests
gptkbp:bfsParent gptkb:pancreatic_neuroendocrine_tumors
gptkbp:bfsLayer 6