pancreatic neuroendocrine tumors

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:disease brain tumor
gptkbp:age	adults
gptkbp:alsoKnownAs	gptkb:PanNETs gptkb:islet_cell_tumors
gptkbp:associatedWith	gptkb:tuberous_sclerosis gptkb:multiple_endocrine_neoplasia_type_1 gptkb:neurofibromatosis_type_1 gptkb:von_Hippel-Lindau_disease
gptkbp:canBeBenign	yes
gptkbp:canBeFunctional	yes
gptkbp:canBeMalignant	yes
gptkbp:canBeNonfunctional	yes
gptkbp:canMetastasizeTo	gptkb:bone liver lymph nodes
gptkbp:diagnosedBy	gptkb:CT_scan MRI biopsy chromogranin A test
gptkbp:firstDescribed	1902
https://www.w3.org/2000/01/rdf-schema#label	pancreatic neuroendocrine tumors
gptkbp:ICD-10_code	C25.4
gptkbp:incidence	rare
gptkbp:location	pancreas
gptkbp:malignantPotential	yes
gptkbp:marking	gptkb:chromogranin_A gptkb:neuron-specific_enolase synaptophysin
gptkbp:maySecrete	gptkb:glucagon gptkb:gastrin gptkb:insulin gptkb:somatostatin gptkb:vasoactive_intestinal_peptide
gptkbp:prognosis	variable
gptkbp:riskFactor	family history genetic syndromes
gptkbp:subspecies	Neuroendocrine Tumor
gptkbp:symptom	gptkb:hypoglycemia abdominal pain jaundice weight loss
gptkbp:treatment	gptkb:somatostatin_analogs surgery chemotherapy radiotherapy targeted therapy
gptkbp:bfsParent	gptkb:Afinitor
gptkbp:bfsLayer	5