myelocytomatosis oncogene

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alsoKnownAs gptkb:MYC
gptkbp:associatedWith gptkb:Burkitt_lymphoma
multiple cancers
gptkbp:discoveredBy gptkb:Harold_Varmus
gptkb:J._Michael_Bishop
gptkbp:discoveredIn 1979
gptkbp:encodes gptkb:c-Myc
gptkbp:Entrez_Gene_ID 4609
ENSG00000136997
gptkbp:function transcription factor
gptkbp:HGNC_ID 7553
https://www.w3.org/2000/01/rdf-schema#label myelocytomatosis oncogene
gptkbp:locatedOnChromosome 8q24.21
gptkbp:mutationAssociatedWith translocation
amplification
gptkbp:OMIM 190080
gptkbp:orthologInMouse gptkb:Myc
gptkbp:proteinFamily basic helix-loop-helix leucine zipper (bHLH-LZ)
gptkbp:regulates apoptosis
cell differentiation
cell proliferation
metabolism
cell cycle progression
ribosome biogenesis
gptkbp:UniProtID P01106
gptkbp:bfsParent gptkb:MYCA
gptkbp:bfsLayer 8