manganese superoxide dismutase
GPTKB entity
Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:MnSOD
|
| gptkbp:associatedWith |
oxidative stress
|
| gptkbp:catalyzes |
dismutation of superoxide into oxygen and hydrogen peroxide
|
| gptkbp:cofactor |
manganese
|
| gptkbp:connectsTo |
gptkb:cancer
neurodegenerative diseases cardiovascular diseases |
| gptkbp:discoveredBy |
1973
|
| gptkbp:EC_number |
1.15.1.1
|
| gptkbp:encodedBy |
gptkb:SOD2_gene
|
| gptkbp:foundIn |
mitochondria
|
| gptkbp:function |
antioxidant defense
|
| gptkbp:gene |
gptkb:SOD2
|
| https://www.w3.org/2000/01/rdf-schema#label |
manganese superoxide dismutase
|
| gptkbp:inhibitedBy |
azide
hydroxylamine |
| gptkbp:locatedOnChromosome |
6q25.3
|
| gptkbp:molecularWeight |
~24 kDa per subunit
|
| gptkbp:mutationAssociatedWith |
mitochondrial dysfunction
increased oxidative damage |
| gptkbp:organism |
eukaryotes
|
| gptkbp:PDB |
gptkb:1LUV
|
| gptkbp:presentIn |
gptkb:Bacteria
animals plants archaea |
| gptkbp:structure |
homotetramer in humans
|
| gptkbp:UniProtID |
P04179
|
| gptkbp:bfsParent |
gptkb:superoxide_dismutase_2
|
| gptkbp:bfsLayer |
7
|