|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:vitamin_A_derivative
|
|
gptkbp:actsOn
|
gptkb:signaling_molecule
|
|
gptkbp:administeredBy
|
gptkb:topical_medication
oral medication
|
|
gptkbp:affects
|
gptkb:DVD
cell differentiation
embryonic development
immune function
|
|
gptkbp:ATCCode
|
D10AD02
|
|
gptkbp:binds
|
retinoid X receptor
retinoic acid receptor
|
|
gptkbp:CASNumber
|
302-79-4
|
|
gptkbp:category
|
terpenoids
retinoids
carboxylic acids
|
|
gptkbp:chemicalFormula
|
C20H28O2
|
|
gptkbp:derivedFrom
|
gptkb:vitamin_A
|
|
gptkbp:discoveredBy
|
20th century
|
|
gptkbp:foundIn
|
animals
humans
|
|
gptkbp:has_tautomer
|
retinoate
|
|
gptkbp:isomerOf
|
gptkb:9-cis-retinoic_acid
13-cis-retinoic acid
all-trans-retinoic acid
|
|
gptkbp:IUPACName
|
(all-trans)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
|
|
gptkbp:meltingPoint
|
137–138 °C
|
|
gptkbp:MeSH_ID
|
gptkb:D011470
|
|
gptkbp:metabolism
|
CYP26 enzymes
|
|
gptkbp:molecularWeight
|
300.44 g/mol
|
|
gptkbp:produces
|
retinol oxidation
|
|
gptkbp:PubChem_CID
|
444795
CHEBI:26536
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:relatedTo
|
gptkb:retinol
gptkb:isotretinoin
retinal
|
|
gptkbp:sideEffect
|
skin irritation
photosensitivity
teratogenicity
dry skin
|
|
gptkbp:solubility
|
insoluble in water
soluble in organic solvents
|
|
gptkbp:UNII
|
G2SH0X191U
|
|
gptkbp:usedFor
|
gptkb:acne_treatment
acute promyelocytic leukemia treatment
|
|
gptkbp:bfsParent
|
gptkb:Nuclear_Receptor_(biochemistry)
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Retinoic acid
|