Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
gptkb:D10BA01
|
| gptkbp:brand |
gptkb:isotretinoin
gptkb:Amnesteem gptkb:Claravis gptkb:Sotret |
| gptkbp:chemicalClass |
gptkb:vitamin_A
|
| gptkbp:contraindication |
pregnancy
|
| gptkbp:discoveredIn |
1979
|
| gptkbp:eliminationHalfLife |
10-20 hours
|
| gptkbp:excretion |
urine
feces |
| gptkbp:genericAvailable |
yes
|
| https://www.w3.org/2000/01/rdf-schema#label |
Accutane
|
| gptkbp:legalStatus |
Rx-only
|
| gptkbp:manufacturer |
gptkb:Roche
|
| gptkbp:mechanismOfAction |
reduces sebaceous gland size and sebum production
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
X
|
| gptkbp:prescriptionStatus |
prescription only
|
| gptkbp:riskManagementProgram |
gptkb:iPLEDGE
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
gptkb:depression
birth defects joint pain dry skin chapped lips |
| gptkbp:usedFor |
severe acne
|
| gptkbp:withdrawn |
2009
|
| gptkbp:withdrawnFromMarketIn |
gptkb:United_States
|
| gptkbp:bfsParent |
gptkb:isotretinoin
gptkb:Roaccutane |
| gptkbp:bfsLayer |
7
|