Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:administeredBy |
oral
|
| gptkbp:alternativeName |
gptkb:Accutane
gptkb:Isotretinoin |
| gptkbp:approvedBy |
1982
|
| gptkbp:brand |
gptkb:isotretinoin
|
| gptkbp:chemicalClass |
gptkb:vitamin_A
|
| gptkbp:contraindication |
pregnancy
|
| gptkbp:form |
capsule
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:manufacturer |
gptkb:Roche
|
| gptkbp:marketedIn |
gptkb:Australia
gptkb:Hong_Kong gptkb:New_Zealand gptkb:South_Africa gptkb:United_Kingdom |
| gptkbp:mechanismOfAction |
decreases sebum production
reduces sebaceous gland size |
| gptkbp:pregnancyCategory |
X
|
| gptkbp:regulates |
prescription only
|
| gptkbp:requiresMonitoring |
liver function
pregnancy tests lipid levels |
| gptkbp:sideEffect |
gptkb:depression
joint pain teratogenicity dry skin |
| gptkbp:usedFor |
severe acne
|
| gptkbp:bfsParent |
gptkb:Roche
|
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
Roaccutane
|