interleukin-5 receptor alpha (IL-5Rα)
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cell surface receptor |
| gptkbp:alternativeName |
gptkb:CD125
IL5R alpha chain |
| gptkbp:associatedWith |
asthma
eosinophilic disorders |
| gptkbp:binds |
gptkb:interleukin-5
|
| gptkbp:component |
gptkb:interleukin-5_receptor
|
| gptkbp:encodedBy |
gptkb:IL5RA_gene
|
| gptkbp:Entrez_Gene_ID |
3568
|
| gptkbp:expressedIn |
gptkb:basophils
gptkb:eosinophils |
| gptkbp:formsComplexWith |
common beta chain (CSF2RB)
|
| gptkbp:function |
mediates IL-5 signaling
regulates eosinophil activation regulates eosinophil survival |
| gptkbp:gene |
IL5RA
|
| gptkbp:HGNC_ID |
HGNC:6027
|
| https://www.w3.org/2000/01/rdf-schema#label |
interleukin-5 receptor alpha (IL-5Rα)
|
| gptkbp:locatedOnChromosome |
chromosome 3p26.2
|
| gptkbp:OMIM |
147851
|
| gptkbp:target |
gptkb:benralizumab
gptkb:mepolizumab gptkb:reslizumab |
| gptkbp:UniProtID |
Q01344
|
| gptkbp:bfsParent |
gptkb:benralizumab
|
| gptkbp:bfsLayer |
7
|