interleukin-2 receptor subunit gamma protein

URI: https://gptkb.org/entity/interleukin-2_receptor_subunit_gamma_protein
GPTKB entity
Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:IL2RG
gptkbp:component interleukin-15 receptor complex
interleukin-2 receptor complex
interleukin-21 receptor complex
interleukin-4 receptor complex
interleukin-7 receptor complex
interleukin-9 receptor complex
gptkbp:discoveredIn 1993
gptkbp:expressedIn lymphocytes
gptkbp:function immune system regulation
cytokine receptor activity
gptkbp:gene gptkb:IL2RG_gene
gptkbp:hasCytoplasmicDomain true
gptkbp:hasExtracellularDomain true
https://www.w3.org/2000/01/rdf-schema#label interleukin-2 receptor subunit gamma protein
gptkbp:interactsWith gptkb:interleukin-2
gptkb:interleukin-9
gptkb:interleukin-4
gptkb:interleukin-15
interleukin-21
interleukin-7
gptkbp:involvedIn gptkb:JAK-STAT_signaling_pathway
gptkbp:locatedOnChromosome gptkb:X_chromosome
gptkbp:location gptkb:cell_membrane
gptkbp:molecularWeight 42 kDa
gptkbp:mutationAssociatedWith gptkb:X-linked_severe_combined_immunodeficiency_(SCID)
gptkbp:OMIM 308380
gptkbp:orthologInChimpanzee gptkb:IL2RG
gptkbp:orthologInMouse gptkb:Il2rg
gptkbp:requires cytokine signaling
lymphocyte development
B cell function
T cell function
NK cell function
gptkbp:transmembraneDomains true
gptkbp:UniProtID P31785
gptkbp:bfsParent gptkb:IL2RG
gptkbp:bfsLayer 7