Statements (67)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Cell
|
| gptkbp:associated_with |
autoimmune diseases
|
| gptkbp:can_be_administered_as |
gptkb:protein
|
| gptkbp:discovered_by |
gptkb:Robert_G._Miller
|
| gptkbp:enhances |
cytokine production
antibody production cytotoxic T cell activity |
| gptkbp:function |
stimulates the growth of T cells
|
| gptkbp:has_impact_on |
tumor growth
|
| gptkbp:has_role |
antiviral responses
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL2
|
| gptkbp:increased |
B cell proliferation
|
| gptkbp:influences |
immune tolerance
|
| gptkbp:initiated_by |
B cells
|
| gptkbp:interacts_with |
IL2 receptor
|
| gptkbp:involved_in |
immune response
cell-mediated immunity |
| gptkbp:is_associated_with |
T cell proliferation
chronic infections T cell memory T cell exhaustion |
| gptkbp:is_essential_for |
T cell homeostasis
|
| gptkbp:is_involved_in |
gptkb:disease
pathogen clearance T cell activation tumor microenvironment tumor immunity immune checkpoint blockade immune cell trafficking cellular immunity vaccine responses immune surveillance immune cell differentiation immune checkpoint regulation immune activation immune regulation host defense mechanisms allergic responses cytokine signaling. |
| gptkbp:is_linked_to |
chronic inflammation
immune response modulation cancer immunotherapy Th2 response immune dysregulation Th1 response |
| gptkbp:is_part_of |
immune system
|
| gptkbp:is_regulated_by |
transcription factors
|
| gptkbp:is_used_in |
clinical trials
combination therapies adoptive cell transfer therapy |
| gptkbp:measures |
gptkb:ELISA
|
| gptkbp:participated_in |
Treg cells
|
| gptkbp:produced |
inflammatory responses
|
| gptkbp:produced_by |
gptkb:T_cells
dendritic cells lymph nodes |
| gptkbp:produces |
NK cells
|
| gptkbp:promoter |
IL2 gene
|
| gptkbp:regulates |
lymphocyte activation
|
| gptkbp:research_areas |
treatment of certain cancers
|
| gptkbp:role |
T cell differentiation
|
| gptkbp:security |
gptkb:CD4+_T_cells
activated T cells |
| gptkbp:targets |
cancer therapies
|
| gptkbp:used_in |
gptkb:immunotherapy
|
| gptkbp:bfsParent |
gptkb:Il-2
|
| gptkbp:bfsLayer |
6
|