|
gptkbp:instanceOf
|
cytokine
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:clinicalTrialPhase
|
gptkb:cancer
|
|
gptkbp:discoveredBy
|
1994
|
|
gptkbp:encodedBy
|
gptkb:IL15_gene
|
|
gptkbp:Entrez_Gene_ID
|
3600
ENSG00000164136
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:placenta
spleen
|
|
gptkbp:function
|
immune system regulation
B cell proliferation
T cell proliferation
NK cell activation
|
|
gptkbp:GO
|
gptkb:GO:0005125
|
|
gptkbp:HGNC_ID
|
5978
|
|
gptkbp:homology
|
gptkb:mouse_IL-15
gptkb:rat_IL-15
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
interleukin-15 (IL-15)
|
|
gptkbp:KEGGID
|
hsa:3600
|
|
gptkbp:length
|
162 amino acids
|
|
gptkbp:locatedOnChromosome
|
4q31
|
|
gptkbp:molecularWeight
|
14-15 kDa
|
|
gptkbp:OMIM
|
600554
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
4GS7
|
|
gptkbp:postTranslationalModification
|
disulfide bonds
glycosylation
|
|
gptkbp:producedBy
|
dendritic cells
macrophages
fibroblasts
monocytes
epithelial cells
|
|
gptkbp:promotion
|
gptkb:NK_cells
memory CD8+ T cells
|
|
gptkbp:Reactome
|
R-HSA-449147
|
|
gptkbp:recipient
|
gptkb:IL-15_receptor
|
|
gptkbp:RefSeq
|
NM_000585
|
|
gptkbp:relatedTo
|
gptkb:interleukin-2
|
|
gptkbp:role
|
infectious diseases
immunotherapy
autoimmune diseases
inflammatory response
|
|
gptkbp:structure
|
four alpha-helix bundle
|
|
gptkbp:symbol
|
gptkb:IL-15
|
|
gptkbp:UniProtID
|
P40933
|
|
gptkbp:bfsParent
|
gptkb:NKp44
|
|
gptkbp:bfsLayer
|
8
|