interferon regulatory factor family
GPTKB entity
Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
IRF family
|
| gptkbp:discoveredBy |
Tada Taniguchi
|
| gptkbp:domain |
DNA-binding domain
IRF-association domain |
| gptkbp:firstDescribed |
1988
|
| gptkbp:foundIn |
mammals
vertebrates |
| gptkbp:function |
regulation of immune response
transcriptional regulation regulation of interferon expression |
| gptkbp:GO_term |
GO:0003700
|
| https://www.w3.org/2000/01/rdf-schema#label |
interferon regulatory factor family
|
| gptkbp:member |
gptkb:IRF5
gptkb:IRF6 gptkb:IRF4 gptkb:IRF9 gptkb:IRF3 gptkb:IRF7 IRF2 IRF1 IRF8 |
| gptkbp:regulates |
antiviral response
immune cell differentiation type I interferon genes |
| gptkbp:relatedTo |
innate immunity
adaptive immunity viral infection response cytokine signaling |
| gptkbp:bfsParent |
gptkb:IRF5
|
| gptkbp:bfsLayer |
8
|