Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antiretroviral therapy
|
| gptkbp:approvedBy |
2007
|
| gptkbp:category |
HIV integrase strand transfer inhibitors (INSTIs)
|
| gptkbp:combines |
gptkb:NNRTIs
gptkb:NRTIs protease inhibitors |
| gptkbp:concerns |
HIV mutation
|
| gptkbp:drugClass |
antiretroviral therapy
|
| gptkbp:example |
gptkb:cabotegravir
gptkb:dolutegravir gptkb:elvitegravir gptkb:raltegravir bictegravir |
| https://www.w3.org/2000/01/rdf-schema#label |
integrase inhibitors
|
| gptkbp:mechanismOfAction |
inhibit HIV integrase enzyme
|
| gptkbp:routeOfAdministration |
injection
oral |
| gptkbp:sideEffect |
nausea
headache insomnia |
| gptkbp:target |
gptkb:HIV-1_integrase
gptkb:HIV-2_integrase |
| gptkbp:usedFor |
HIV treatment
|
| gptkbp:WHOStatus |
gptkb:Essential_Medicines
|
| gptkbp:bfsParent |
gptkb:HIV_integrase
gptkb:integrase |
| gptkbp:bfsLayer |
6
|