hydroxycarboxylic acid receptors

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:G_protein-coupled_receptor
gptkbp:alternativeName GPR81/109A/109B
HCAR family
gptkbp:binds hydroxycarboxylic acids
gptkbp:discoveredBy F. Offermanns
gptkbp:discoveredIn 2008
gptkbp:expressedIn adipose tissue
immune cells
gptkbp:foundIn mammals
gptkbp:function regulation of lipid metabolism
inhibition of lipolysis
https://www.w3.org/2000/01/rdf-schema#label hydroxycarboxylic acid receptors
gptkbp:includes HCAR1
HCAR2
HCAR3
gptkbp:ligand gptkb:nicotinic_acid
lactate
3-hydroxybutyric acid
gptkbp:locatedOnChromosome gptkb:chromosome_12_(human)
gptkbp:proteinFamily gptkb:GPCR
gptkbp:relatedTo energy homeostasis
gptkbp:subclassOf cell surface receptor
gptkbp:bfsParent gptkb:G_protein-coupled_receptor_superfamily
gptkbp:bfsLayer 7