histamine methyltransferase

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:enzyme
gptkbp:alternativeName	gptkb:HNMT histamine N-methyltransferase
gptkbp:associatedWith	allergic diseases histamine metabolism asthma susceptibility allergic response regulation
gptkbp:biologicalProcess	methyltransferase activity histamine catabolic process
gptkbp:catalyzes	methylation of histamine
gptkbp:cofactor	gptkb:S-adenosyl-L-methionine
gptkbp:EC_number	2.1.1.8
gptkbp:foundIn	gptkb:kidney central nervous system liver cytosol
gptkbp:function	inactivates histamine
gptkbp:gene	gptkb:HNMT
gptkbp:inhibitedBy	gptkb:metoprine gptkb:quinacrine
gptkbp:length	292 amino acids
gptkbp:locatedOnChromosome	2q22.1
gptkbp:OMIM	601922
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:product	gptkb:N-methylhistamine gptkb:S-adenosyl-L-homocysteine
gptkbp:structure	monomeric protein
gptkbp:substrate	gptkb:histamine
gptkbp:UniProtID	gptkb:P50135
gptkbp:bfsParent	gptkb:histamine-N-methyltransferase
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	histamine methyltransferase