Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
antiviral drug dye antineoplastic agent |
| gptkbp:ATCCode |
P01BA02
|
| gptkbp:brand |
Atabrine
|
| gptkbp:CASNumber |
83-89-6
|
| gptkbp:category |
dye
antimalarial anthelmintic antiprotozoal DNA intercalator acridine derivative antirheumatic agent |
| gptkbp:chemicalFormula |
C23H30ClN3O
|
| gptkbp:color |
yellow
|
| gptkbp:discoveredBy |
I.G. Farben
|
| gptkbp:excretion |
gptkb:kidney
|
| gptkbp:firstSynthesized |
1931
|
| https://www.w3.org/2000/01/rdf-schema#label |
quinacrine
|
| gptkbp:IUPACName |
N'-(6-chloro-2-methoxyacridin-9-yl)-N,N-diethylpentane-1,4-diamine
|
| gptkbp:KEGGID |
D08441
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
intercalates into DNA
inhibits phospholipase A2 |
| gptkbp:meltingPoint |
174–175 °C
|
| gptkbp:MeSH_ID |
D011789
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
399.96 g/mol
|
| gptkbp:pKa |
10.3
|
| gptkbp:PubChem_CID |
237
CHEMBL1536 DB01103 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
headache
psychosis gastrointestinal upset yellow discoloration of skin |
| gptkbp:solubility |
slightly soluble in water
|
| gptkbp:UNII |
D72O4R1U1B
|
| gptkbp:used_in |
gptkb:World_War_II
|
| gptkbp:usedFor |
treatment of malaria
treatment of giardiasis non-surgical sterilization (off-label) treatment of lupus erythematosus treatment of tapeworm infection |
| gptkbp:bfsParent |
gptkb:histamine-N-methyltransferase
|
| gptkbp:bfsLayer |
8
|