|
gptkbp:instanceOf
|
gptkb:coenzyme
biochemical compound
|
|
gptkbp:abbreviation
|
gptkb:AdoMet
gptkb:SAM
|
|
gptkbp:biosynthesized_from
|
gptkb:ATP
methionine
|
|
gptkbp:CASNumber
|
29908-03-0
|
|
gptkbp:category
|
amino acid derivative
nucleoside
sulfonium compound
|
|
gptkbp:chemicalFormula
|
C15H22N6O5S
|
|
gptkbp:contraindicated_with
|
gptkb:Parkinson's_disease
bipolar disorder
|
|
gptkbp:decarboxylated_to
|
decarboxylated S-adenosylmethionine
|
|
gptkbp:degradedBy
|
gptkb:S-adenosylhomocysteine
|
|
gptkbp:discoveredBy
|
gptkb:Giulio_Cantoni
|
|
gptkbp:discoveredIn
|
1952
|
|
gptkbp:enzyme_for_biosynthesis
|
gptkb:methionine_adenosyltransferase
|
|
gptkbp:foundIn
|
all domains of life
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
S-adenosyl-L-methionine
|
|
gptkbp:IUPACName
|
S-(5'-deoxyadenosyl)-L-methionine
|
|
gptkbp:MeSH_ID
|
D012446
|
|
gptkbp:molecularWeight
|
398.44 g/mol
|
|
gptkbp:pathway
|
transsulfuration pathway
methionine cycle
polyamine biosynthesis
transmethylation pathway
|
|
gptkbp:PubChem_CID
|
34755
CHEBI:16810
|
|
gptkbp:role
|
methyl group donor
precursor in biosynthesis of polyamines
precursor in biosynthesis of ethylene
precursor in biosynthesis of trans-methylation reactions
|
|
gptkbp:sideEffect
|
anxiety
insomnia
gastrointestinal upset
|
|
gptkbp:solubility
|
water soluble
|
|
gptkbp:used_as_supplement_for
|
gptkb:depression
gptkb:liver_disease
osteoarthritis
|
|
gptkbp:used_in
|
methylation of DNA
methylation of RNA
methylation of lipids
methylation of proteins
|
|
gptkbp:used_in_medicine_as
|
dietary supplement
|
|
gptkbp:bfsParent
|
gptkb:S-adenosyl_methionine
gptkb:S-Adenosyl_methionine_(SAMe)
gptkb:SAM_E
|
|
gptkbp:bfsLayer
|
7
|