hepatocyte growth factor receptor

URI: https://gptkb.org/entity/hepatocyte_growth_factor_receptor
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alsoKnownAs gptkb:c-Met
gptkbp:binds hepatocyte growth factor
gptkbp:discoveredBy gptkb:George_F._Vande_Woude
gptkbp:discoveredIn 1984
gptkbp:domain tyrosine kinase domain
immunoglobulin-plexin-transcription (IPT) domain
semaphorin domain
gptkbp:encodedBy gptkb:MET_gene
gptkbp:expressedIn endothelial cells
epithelial cells
gptkbp:function gptkb:receptor_tyrosine_kinase
gptkbp:gene gptkb:MET
gptkbp:HGNC_ID 7029
https://www.w3.org/2000/01/rdf-schema#label hepatocyte growth factor receptor
gptkbp:involvedIn wound healing
morphogenesis
angiogenesis
cancer progression
cell growth
cell motility
gptkbp:locatedOnChromosome gptkb:chromosome_7
gptkbp:mutationAssociatedWith gptkb:cancer
hepatocellular carcinoma
gastric cancer
papillary renal carcinoma
gptkbp:OMIM 164860
gptkbp:phosphorylates tyrosine residues
gptkbp:structure single-pass transmembrane protein
gptkbp:target targeted cancer therapies
gptkbp:UniProtID P08581
gptkbp:bfsParent gptkb:c-Met
gptkbp:bfsLayer 6