|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:ERG1
Ether-à-go-go potassium channel
Kv11.1
|
|
gptkbp:associatedWith
|
long QT syndrome
|
|
gptkbp:discoveredBy
|
gptkb:Mark_Keating
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:encodes
|
Kv11.1 potassium channel
|
|
gptkbp:expressedIn
|
heart
|
|
gptkbp:fullName
|
human Ether-à-go-go-Related Gene
|
|
gptkbp:function
|
potassium ion transport
|
|
gptkbp:gene
|
gptkb:KCNH2
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6251
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
hERG
|
|
gptkbp:inhibitedBy
|
many drugs
|
|
gptkbp:locatedOnChromosome
|
7
|
|
gptkbp:mutationAssociatedWith
|
gptkb:arrhythmia
|
|
gptkbp:OMIM
|
152427
|
|
gptkbp:orthologInMouse
|
gptkb:Kcnh2
|
|
gptkbp:proteinFamily
|
voltage-gated potassium channels
|
|
gptkbp:relatedTo
|
gptkb:ventricular_fibrillation
gptkb:torsades_de_pointes
cardiac repolarization
|
|
gptkbp:significance
|
drug-induced QT prolongation
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
six transmembrane domains
|
|
gptkbp:UniProtID
|
gptkb:Q12809
|
|
gptkbp:bfsParent
|
gptkb:O60500
|
|
gptkbp:bfsLayer
|
7
|